Which of the following is a sign of infection?

The presence of fever and rash is a significant sign of infection. Infections often trigger the body's immune response, leading to an elevation in body temperature, which manifests as a fever. This is a natural defense mechanism aimed at creating an environment less favorable for pathogens. Additionally, a rash can indicate the skin's response to an infectious agent, whether that be a bacteria, virus, or another irritant. The combination of these symptoms can suggest that the body is actively responding to an infection, making it critical for health care professionals to monitor and address these signs promptly.

In contrast, increased appetite typically indicates good health and well-being, while enhanced energy levels suggest that the body is not fighting off an illness. Similarly, a stable pulse rate generally signifies that the body is functioning normally and not in distress, which would be expected in the presence of an infection. Each of these factors points away from infection, emphasizing the importance of fever and rash in identifying potential health issues.